Search reports, ask a question, or jump to a page.
The problem
Intervention: No intervention was tested; this is an observational study examining the association between natural infection and nutritional outcomes
Who it was tested with: Children under 2 years old in seven countries (Bangladesh, Brazil, India, Nepal, Peru, South Africa, Tanzania) enrolled in the MAL-ED longitudinal birth cohort study.
Children or communities are compared with a group that did not receive the intervention, or followed over years. This is the design that best separates what the intervention did from everything else that changed.
"This is a secondary analysis of data from the MAL-ED study which is a longitudinal birth cohort study conducted in eight countries... a multi-country investigation of enteric infections and malnutrition. We excluded Pakistan due to the lack of available anthropometric data." The study uses a longitudinal cohort design with repeated measurements and generalized estimating equations to assess associations between infection exposure and nutritional outcomes across time.
Secondary analysis without experimental manipulation; observational associations cannot prove causation; differences in incidence across countries suggest uncontrolled contextual variables; no intervention tested, only exposure-outcome association examined
Across countries and designs
40 studies · 42 countries
