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The problem
Intervention: Influenza vaccination
Who it was tested with: 194 post-operative children with congenital heart disease in Shanghai, China (January–July 2023); 21.6% were vaccinated.
Children or communities are compared with a group that did not receive the intervention, or followed over years. This is the design that best separates what the intervention did from everything else that changed.
"The primary analysis used doubly robust quasi-Poisson regression on an IPTW pseudo-population." This statement demonstrates the use of an advanced quasi-experimental design with both propensity score weighting and regression adjustment to minimise confounding, which qualifies as an experimental approach to observational data.
Retrospective design; small sample size with low vaccination coverage (21.6%); single-city setting and limited time period (6 months); potential for residual confounding despite IPTW methods
Across countries and designs
3 studies · 3 countries
