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The problem
Intervention: Observational assessment of the prevalence and patterns of alternative vaccination schedules in real-world clinical practice, combined with qualitative interviews exploring parental motivations and provider perspectives
Who it was tested with: Children in Israel aged 12 months through primary vaccination series completion (pertussis series); parents, maternal and child health clinic providers, and policymakers in Israel.
The same group is measured before the intervention and again afterwards, with a baseline and an endline and sometimes a midline. Change is visible, but other causes cannot be ruled out.
"A mixed-methods design was employed: a retrospective cohort analysis of vaccination data from 2018 to 2021 (before and during the COVID-19 pandemic) focused on measles (first dose at 12 months) and pertussis (four-dose primary series), followed by semi-structured interviews with Maternal and Child Health clinic providers, policymakers, and parents." The study documents real-world vaccination patterns and their consequences, showing that alternative schedules result in delays and incomplete protection, indicating that this approach to vaccination does not improve child health outcomes.
This is an observational study without a randomized control group or measurement of actual disease outcomes. The study documents patterns and perceptions but does not establish causal links between alternative schedules and specific health harms, nor does it compare health outcomes between alternative and standard schedules.
Across countries and designs
2 studies · 2 countries
