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The problem
Intervention: Oral nutritional supplements (ONS) providing approximately 412 kcal and 16.3 g protein daily
Who it was tested with: 1116 children with faltering growth or at risk of it, weighted mean age 5 years, 59% male.
Children or communities are compared with a group that did not receive the intervention, or followed over years. This is the design that best separates what the intervention did from everything else that changed.
"Ten randomised controlled trials (RCTs), compared changes in outcomes amongst children receiving ONS versus control were included." The systematic review pooled results from multiple RCTs with comparison groups, representing the strongest study design tier for evaluating intervention effectiveness.
Review does not specify countries where trials were conducted. Limited information on long-term effects or optimal dosage. Heterogeneity between trials not fully explored.
Across countries and designs
3 studies · 2 countries
