Peer-reviewed article
Testing the clinical application of the child psychosis-risk screening system (CPSS)
Hamasaki Y, Matsuo M, Sakaue Y, Sanada R, Nakayama T et al. ·
Summary
Written by AI, not yet AICS's view · claude-haiku-4-5-20251001This study tested a screening tool called the Child Psychosis-Risk Screening System (CPSS) to identify children aged 6-14 who may be at risk of developing psychosis. Researchers examined 204 children seen at pediatric and psychiatric clinics, using a behavioral assessment tool and medical records. The study found that environmental factors like abuse and social isolation were more helpful for identifying at-risk children than their current diagnosis or physical complaints. The authors suggest that some high-risk children may have an underlying vulnerability to psychosis that has not yet appeared.
Key points
- A screening system was developed to identify children in a prodromal state who may develop psychosis
- Environmental factors of abuse and social isolation contributed significantly to identifying high-risk children
- Current diagnostic category and chief complaint did not help distinguish between high-risk and low-risk groups
- The study involved 204 outpatients aged 6-14 years evaluated at pediatric or psychiatric clinics
- Results suggest high-risk children may have a latent vulnerability not yet manifested as symptoms
Limitations
The study does not report long-term follow-up data to confirm whether identified high-risk children actually develop psychosis. The document does not specify the geographic location or population characteristics, limiting understanding of generalizability.
Abstract
Introduction Children in a prodromal state manifesting as truancy or social isolation (hikikomori) often complain of problems that are physical in nature and are subject to significant changes. We developed the Child Psychosis-Risk Screening System (CPSS) that incorporates childhood psycho-behavioral characteristics revealed through a retrospective survey of schizophrenia patients into its algorithm. Objectives Our research aimed to test the risk identification of pediatric and psychiatric clinic outpatients using the CPSS. Methods We conducted an epidemiological study involving 204 outpatients between the ages of 6 and 14 years who had been examined at a pediatric or psychiatric clinic using the CBCL and clinical data from medical charts. Logistic regression analysis and T-tests were performed using each clinical data variable to clarify the risk of the CPSS calculated from the CBCL data and contributing factors. Results The results of the logistic regression analysis demonstrated that the diagnostic category (physical illness or DSM-5 diagnosis) and chief complaint did not contribute to differentiate between the high-risk and low-risk groups. Meanwhile, the environmental factors of “abuse” and “social isolation” did contribute to the discrimination of the two groups. Conclusions The fact that the diagnostic category during childhood does not contribute to the discrimination of the high- risk group warrants attention. It is possible that the high-risk group only had a latent endophenotype that had not yet manifested during this period. The factors suggested to have an association with the high-risk group may be reflecting activators and the dynamic state of the critical period for psychosis. Disclosure No significant relationships.
Findings the Hub has extracted
Each claim below is labelled by its type of design and links back to this report.
- Intervention
- Application of the Child Psychosis-Risk Screening System (CPSS) using the Child Behavior Checklist (CBCL) and clinical data from medical charts
- Population
- 204 outpatients aged 6-14 years examined at pediatric or psychiatric clinics
Key finding
Environmental factors of abuse and social isolation significantly contributed to discrimination between high-risk and low-risk groups
Y et al. · PubMed Central (PMC) · 13 Aug 2021