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The problem
Intervention: Ensuring vaccine availability (measured by absence of national-level stockouts)
Who it was tested with: Children in 131 low-income and middle-income countries, 2004-2019.
Children or communities are compared with a group that did not receive the intervention, or followed over years. This is the design that best separates what the intervention did from everything else that changed.
"A retrospective cohort study" of "131 low-income and middle-income countries from 2004 to 2019" comparing immunisation coverage "between the countries that experienced national-level stockouts" and those without. The design used longitudinal national data to measure associations between stockout events and coverage outcomes.
Study found statistically significant associations between stockouts and coverage but not with mortality outcomes; cannot rule out confounding factors; retrospective design limits causal inference; does not examine mechanisms linking stockouts to coverage gaps
Across countries and designs
1 study · 1 country