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The problem
Intervention: Hydroxyurea therapy, compared with no hydroxyurea
Who it was tested with: 110 children aged 2-17 years with sickle cell anaemia attending Wesley Guild Hospital, Ilesa, Nigeria.
Experience from people who deliver programmes: stories, case studies and lessons learned. Valuable for understanding how and why, and for spotting what to test next, but not a measure of effect.
"This cross-sectional comparative study included 110 children with SCA aged 2-17 years" shows a single-time-point comparison rather than a randomised, quasi-experimental or longitudinal design, so the lower tier is chosen.
Cross-sectional, single-site design; no before-and-after measurement or randomisation, so causal effects cannot be determined. Details on group selection, dose and treatment duration are not given in the abstract.
Across countries and designs
1 study · 1 country
