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The problem
Intervention: Family Nurture Care (FNC): structured calming sessions approximately 3 times per week where mothers engage in emotional expression, skin-to-skin or clothed holding, vocal soothing, and eye contact with their preterm infants, facilitated by nurture specialists
Who it was tested with: Preterm infants born at 25-34 weeks gestational age and their mothers in a single-center NICU (Phase I SC: n=34 at 35 weeks, n=28 at term; Phase II FNC: n=28 at 35 weeks, n=27 at term).
The same group is measured before the intervention and again afterwards, with a baseline and an endline and sometimes a midline. Change is visible, but other causes cannot be ruled out.
"In Phase I, all mother-infant dyads received the baseline standard care (SC), and in Phase II, all mother-infant dyads received SC supplemented with FNC starting at NICU admission." The study used a before-after comparison of brain activity in different phases, measuring EEG power as the primary outcome at two timepoints.
Phased design without randomization limits causal inference; temporal trends or other changes between phases could contribute to differences. Single center limits generalizability. Only early brain activity measured; longer-term developmental outcomes not assessed. No comparison of FNC to active control intervention.
Across countries and designs
1 study · 1 country
