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The problem
Intervention: Monthly provision of low-aflatoxin maize and groundnut flour to infants aged 6-18 months, combined with infant and young child feeding education
Who it was tested with: 2,842 maternal-infant dyads in rural Kongwa District, Tanzania; infants followed from 6 to 18 months of age.
Children or communities are compared with a group that did not receive the intervention, or followed over years. This is the design that best separates what the intervention did from everything else that changed.
"The trial assessed whether a 12-mo intervention to reduce AF consumption increased length-for-age z-scores (LAZ) at 18 mo" through a "cluster-randomized, community-based 2-group trial conducted in Kongwa District, Tanzania, between 2018 and 2020." The randomized design with measurement at multiple timepoints and analysis by intention-to-treat provides experimental evidence, though the inconclusive outcome reflects inadequate exposure variation between groups.
Unexpectedly low aflatoxin exposure levels in both trial arms due to favorable weather and agricultural conditions prevented adequate testing of the intervention. The study cannot determine whether aflatoxin reduction would improve growth under conditions of higher contamination typical of other seasons or years in the region.
Across countries and designs
1 study · 1 country
