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The problem
Intervention: Anti-rabies vaccine (two doses on days 0.7 and 16) without rabies immunoglobulin, plus supportive hospital care
Who it was tested with: 8-year-6-month-old child in rural northeastern Uganda bitten by stray dog.
Experience from people who deliver programmes: stories, case studies and lessons learned. Valuable for understanding how and why, and for spotting what to test next, but not a measure of effect.
"Paralytic rabies in children can be fatal even after vaccination, especially if rabies immunoglobulin is not given when there is a high risk exposure." This demonstrates the critical importance of complete post-exposure prophylaxis (vaccine plus immunoglobulin) in preventing rabies mortality, even in vaccinated individuals.
Single case report without laboratory confirmation of rabies diagnosis, no comparison group, limited ability to determine whether vaccine failure or incomplete regimen was the primary cause of death
Across countries and designs
1 study · 1 country
