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The problem
Intervention: Repeated low-intensity red light (RLRL) therapy combined with DIMS spectacles
Who it was tested with: 100 children with persistent myopia progression despite DIMS spectacle wear; 92 completed 12-month follow-up (50 in combination group, 42 in control group).
Children or communities are compared with a group that did not receive the intervention, or followed over years. This is the design that best separates what the intervention did from everything else that changed.
"In this retrospective cohort study, medical records of 100 children with persistent myopia progression despite DIMS spectacle wear were reviewed. Patients were divided into two groups based on their treatment history: a DIMS-only control group (n=50) and an RLRL+DIMS combination group (n=50)." This indicates a comparison of two cohorts followed over time with multiple outcome measurements, placing it at the EXPERIMENTAL tier despite being retrospective rather than randomized.
Retrospective design without randomization; 8% loss to follow-up; single-site study; limited follow-up duration of 12 months; minimal adverse event reporting detail
Across countries and designs
1 study · 0 countries