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The problem
Intervention: Group-cognitive behavioral therapy (G-CBT) and multiple family group (MFG) therapy sessions delivered over 3 months, compared to usual care
Who it was tested with: Adolescents aged 10-14 years living with HIV and taking antiretroviral therapy, living with a family in Uganda (89 participants; 147 screened).
Children or communities are compared with a group that did not receive the intervention, or followed over years. This is the design that best separates what the intervention did from everything else that changed.
"We used mixed-effects logistic regression analysis to examine the effect of the interventions on ART adherence. Pairwise comparisons showed increasing adherence in the MFG group compared to usual care at visit 3... Also, compared to usual care, participants who received G-CBT showed higher adherence at visit 4." The study employed a cluster-randomized design with comparison groups and multiple measurement points, meeting the criteria for an experimental design with objective adherence measurement through pharmacy records.
Small pilot sample (89 participants) limits generalizability; short follow-up period (4 months); 3 participants lost to follow-up and 1 death; unclear whether effects persist beyond the intervention period; no information on baseline adherence levels or reasons for non-adherence.
Across countries and designs
1 study · 1 country
