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The problem
Intervention: Oral rotavirus vaccine (complete series)
Who it was tested with: Malnourished and well-nourished children in 19 medium to high child mortality countries.
Experience from people who deliver programmes: stories, case studies and lessons learned. Valuable for understanding how and why, and for spotting what to test next, but not a measure of effect.
"We calculated complete series rotavirus VE in each malnourished and well-nourished group using an unconditional adjusted logistic regression model, where VE = (1 - odds ratio of vaccination among cases and controls) × 100, where cases and controls were children who tested rotavirus positive and negative, respectively." The study uses a comparison group design with stratified analysis by nutritional status to evaluate vaccine effectiveness under different conditions.
The analysis is observational rather than randomized, so residual confounding cannot be excluded. Wide confidence intervals in the severe stunting group (-14 to 58) indicate imprecision in this subgroup estimate. The specific countries and vaccines are not identified in the provided abstract.
Across countries and designs
1 study · 0 countries
A reviewer checked the classification against the source.
claude-haiku-4-5-20251001 · synth-v1
