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The problem
Intervention: Screening of all pregnant women at first antenatal care visit for HBV and HCV using rapid testing; linkage to care and tenofovir disoproxil fumarate prophylaxis for HBV-positive women; implementation of daily hepatitis B birth dose vaccination in healthcare facilities
Who it was tested with: 2,844 pregnant women attending antenatal care and their newborns at five public health facilities in Delta State, Nigeria.
The same group is measured before the intervention and again afterwards, with a baseline and an endline and sometimes a midline. Change is visible, but other causes cannot be ruled out.
"The project design was a prospective implementation research which involved a cohort of pregnant women registered for ANC in the five pilot healthcare facilities" with measurement of HepB-BD vaccination coverage and timeliness pre- and post-intervention using "paired t-tests and Chi-squared" statistical analysis. This design allowed measurement of outcomes before and after the intervention was implemented, establishing a pre-post comparison within the same facilities.
The study used a single-arm pre-post design without a comparison group, making it difficult to attribute improvements solely to the intervention. Selection bias may exist if the five pilot facilities are not representative of all facilities in Delta State. Long-term maternal and child health outcomes were not measured.
Across countries and designs
1 study · 1 country
