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The problem
Intervention: Introduction of two-dose varicella vaccination strategy and public health and social measures (PHSMs)
Who it was tested with: Children aged 0-14 years in Quzhou City, China.
Experience from people who deliver programmes: stories, case studies and lessons learned. Valuable for understanding how and why, and for spotting what to test next, but not a measure of effect.
"An interrupted time-series (ITS) model was used to analyze trends in monthly varicella incidence during the implementation of the single-dose and two-dose vaccination strategies and the PHSMs." The study measured incidence before and after intervention introduction but lacks a comparison group, making it a pre-post design that can show associations but not prove causation.
Interrupted time-series design without randomization or control group; cannot rule out other confounding factors affecting varicella trends; single-city setting limits generalizability; coverage data suggests implementation fidelity issues.
Across countries and designs
5 studies · 3 countries
