Peer-reviewed article
Efficacy and Safety of Oral Probiotics in Children with Allergic Rhinitis: A Review
Angela Klain, Giulio Dinardo, Cristiana Indolfi, Marcella Contieri, Alessandra Salvatori et al. ·
Summary
Written by AI, not yet AICS's view · claude-haiku-4-5-20251001This review examines how probiotics might help children with allergic rhinitis, a condition that affects their quality of life and growth. The research explores the role of gut bacteria (microbiota) in allergic diseases, particularly how imbalances in bacterial composition may contribute to allergic rhinitis. The review discusses how probiotics could restore healthy gut bacteria and help rebalance the immune system to improve allergic symptoms. The study also covers the connection between gut and lung health in children.
Key points
- Allergic rhinitis prevalence is rising and impacts children's growth and quality of life
- Dysbiosis (impaired microbiota composition) characterizes allergic disorders in children
- Probiotics may restore gut dysbiosis and rebalance immune response in children
- The gut–lung axis plays a role in children's allergic diseases
- Probiotics may indirectly influence the clinical course of allergic diseases
Limitations
This is a review article that synthesizes existing literature rather than presenting new empirical data. It cannot provide definitive evidence about the efficacy and safety of probiotics in children with allergic rhinitis without examining the specific studies cited.
Abstract
The prevalence of allergic rhinitis is rising, and it is impacting children’s growth and quality of life. To uncover unconventional treatment modalities, research was carried out to clarify the significance of novel components in the pathophysiology of allergic rhinitis. One of these elements was gut microbiota, which plays a crucial role in the development and evolution of allergic disorders. Specifically, dysbiosis, defined as impaired microbiota composition, characterizes allergic disorders. In light of this concept, probiotics (beneficial bacteria) may restore gut dysbiosis, rebalance the immune response, and indirectly influence the clinical course of allergic diseases. In this article, we discussed the role of the gut–lung axis in children and reported on new findings. We also reviewed the most relevant studies about probiotics in patients with allergic rhinitis.