Peer-reviewed article
Pathopsychological assessment of pediatric patients with autoimmune diseases of central nervous system
Fedorova J, Burlakova N, Mikadze J, Azizova U ·
Summary
Written by AI, not yet AICS's view · claude-haiku-4-5-20251001This is a clinical case study of two adolescent girls with autoimmune diseases affecting the central nervous system (ADEM and MS). The study uses psychological assessment methods to describe mental and behavioural disturbances in these patients. While the work identifies psychological concerns in children with these neurological conditions, it does not evaluate an intervention to improve child well-being.
Key points
- Both patients showed organic brain disorders but no intellectual deterioration
- The MS patient showed multiple types of mental disorders (polymorphism), while the ADEM patient showed more uniform mental disturbances
- The MS patient had self-regulation problems similar to pseudo-frontal syndrome
- The ADEM patient displayed neurodynamic disturbances similar to psychoorganic syndrome
- Psychological monitoring is recommended to prevent personality disorders
Limitations
This is a descriptive case study of only two individual patients, so findings cannot be generalised to other children with these conditions. The document does not test or evaluate any intervention to improve outcomes.
Abstract
Introduction Autoimmune diseases of central nervous system (CNS) are wide spread in children. In some cases, mental disturbances in such patients are barely noticeable in the beginning, which hinders early detection of risks in the child’s mental development. Objectives The study focuses on comparative analysis of the structure of mental disorders in pediatric patients with autoimmune diseases of CNS. Methods Research includes two cases: girls aged 14 and 16, one with acute disseminated encephalomyelitis (ADEM), disease onset at 4 years and 11 months, and another with multiple sclerosis (MS), disease onset at 5 years and 5 months. The following methods were used: analysis of patient’s medical record, interview with neurologists, pathopsychological assessment. Results Common features in both cases: 1) organic brain disorders; 2) patients do not demonstrate intellectual deterioration, can master regular school curriculum; 3) detected mental disturbances reflect risks for mental and personality development. Specific features: 1) the patient with MS demonstrates polymorphism of mental disorders, while the patient with ADEM — homogeneity of mental disorders; 2) main problems of the patient with MS are related to self-regulation, which makes the general picture similar to pseudo-frontal syndrome; the patient with ADEM has major neurodynamic disturbances, which has similarity to psychoorganic syndrome; 3) predictors of personality disorders detected in case of MS determine the negative prognosis for mental development. Conclusions The delineated features evidence for further psychological study of CNS autoimmune diseases and formulation of criteria for clinical psychological assessment. These patients need to be monitored by psychologists to prevent personality disorders. Disclosure No significant relationships.