Peer-reviewed article
3245 Comparison of Health Outcomes in Adolescent and Young Adult (AYA) Oncology Patients Treated at a Pediatric versus Adult Institute
Moskop A ·
Summary
Written by AI, not yet AICS's view · claude-haiku-4-5-20251001This is a research protocol for a retrospective cohort study comparing health outcomes for adolescents and young adults (ages 15-39) with cancer treated at pediatric versus adult oncology centers. The study will examine differences in clinical care, supportive services, and treatment toxicity between the two settings using data from 2013-2017. While the study concerns young people, it focuses on cancer treatment outcomes rather than child well-being in the broader sense.
Key points
- Study compares AYA cancer patients treated at pediatric versus adult facilities
- Covers common diagnoses including leukemias, lymphomas, sarcomas, and CNS tumors
- Examines differences in clinical trial enrollment and treatment toxicity
- Investigates receipt of supportive care including psychology, social work, and palliative care referrals
- Uses retrospective cohort design with data from 2013-2017
Limitations
This is a study protocol describing anticipated results rather than actual findings, so no empirical outcomes are reported. The document does not specify which countries or institutions are involved beyond reference to 'MCW'.
Abstract
OBJECTIVES/SPECIFIC AIMS: Objectives: To examine the differences in health outcomes of adolescents and young adults treated for malignancy at a pediatric cancer center compared to an adult cancer center. To determine the differences in receipt of supportive care for adolescents and young adults with malignancy who are treated at a pediatric cancer center compared to an adult cancer center. METHODS/STUDY POPULATION: Methods: This will be a retrospective cohort study of patients from the ages of 15 to 39 years who are diagnosed with a malignancy common between adult and pediatric facilities within 2013-2017. Data will be abstracted from an existing database at MCW containing patient information at the adult and pediatric centers. Study population: Patients ages 15-39 years of age who are categorized as young adolescent and adult patients (AYAs). Patients are eligible for the cohort if they have a diagnosis that is common between adult and pediatric oncology centers and that is made within the years 2013-2017. These diagnoses will include ALL, AML, Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Germ cell tumors, Osteosarcoma, Ewing Sarcoma, other sarcomas, and CNS tumors. RESULTS/ANTICIPATED RESULTS: There will be a difference in health care utilization, clinical trial enrollment and toxicity of therapy in AYAs with malignancies treated at an adult facility than AYAs treated for similar malignancy at pediatric facility. DISCUSSION/SIGNIFICANCE OF IMPACT: There will be a difference in receipt of supportive care referrals, including psychology, social work, sperm banking, initiation of palliative care, in AYAs treated at a pediatric facility compared to AYAs treated at adult facility.