Peer-reviewed article
Systematic Review On Covid Vaccination In Children- Assessment Of Safety, Immunogenicity, Efficacy And Adverse Effects
Dr Amandeep Kaur, Dr Navdeep Kaur, Dr Preeti Singh Dhoat, Mohit Madhukar ·
Summary
Written by AI, not yet AICS's view · claude-haiku-4-5-20251001This systematic review examined the safety, immunogenicity, efficacy and adverse effects of COVID-19 vaccines in children. The authors searched available literature to understand how well vaccines work in children compared to adults and whether they cause harm. The review found that COVID-19 vaccines show similar safety and efficacy in children as in adults. However, the authors note that more clinical trials are needed to evaluate long-term effects of the vaccines.
Key points
- Vaccinated individuals who become infected transmit the virus less frequently due to reduced viral load and shorter virus shedding duration
- Transmission from vaccinated individuals to household contacts is significantly lower than from unvaccinated individuals
- Available data reports similar efficacy and safety in children as in adults
- More clinical trials are needed for evaluation of long-term effects of COVID vaccines in children
Limitations
The document is an abstract or summary that does not provide detailed methodology, specific studies reviewed, numerical results, or breakdown of findings by vaccine type or age group. It does not specify which countries' data were included or describe the quantity and quality of evidence examined.
Abstract
Introduction: The recent pandemic outbreak Covid-19 has led to substantial illness and ultimate mortality across the globe and childrenare highly are in the verge of being in a critical role as vectors in the transmission of SARS-CoV-2 in the community. There are quitea few studies which have observed that the vaccinated individuals who become infected again are on the side fewer side to transmit thevirus due to reduced viral load and the duration of virus shedding and as a result, transmission from vaccinated individual to householdcontacts is significantly lower. This systemic review was thus undertaken with the objective of analysing the literature that wereavailable on the safety, immunogenicity, efficacy and if any adverse effects of covid vaccination in children.Material and Methods: We conducted both a systematic review. This review was solely based on the predefined protocol and it wasconducted in concordance with PRISMA guidelines.Conclusion: The available data reports similar efficacy and safety in children as of adults. Therefore, more clinical trials are needed tobe conducted and published for evaluation of safety and if any long-term effects of Covid vaccines.
Findings the Hub has extracted
Each claim below is labelled by its type of design and links back to this report.
Problem
COVID-19 transmission in children and risk of illness and mortality from SARS-CoV-2 infection
- Intervention
- COVID-19 vaccination in children
- Population
- Children
Key finding
COVID-19 vaccines show similar efficacy in children as in adults
Kaur et al. · OpenAlex · 19 Oct 2022