Evidence

Evidence on children's well-being, problem first.

Every finding is tied to a defined problem for children, the intervention that claims to solve it, and its type of design. Open any card to compare the same intervention across countries.

89 evidence items · page 2 of 8

Survival

DEGB

Problem

Corticosteroid-induced side effects and loss of physical capacity in adolescents with leukemia or lymphoma during induction therapy

Intervention: 8-week exercise training during the first weeks of treatment, plus one-time nutrition counselling for all participants, compared with a sham control intervention
Population: Newly diagnosed patients with leukemia or lymphoma aged 10 to 17 years; six completed the trial (two in the intervention group)

Key finding

Feasibility criteria were not met: consent 67%, training adherence 51%, complete measures 70% (target ≥80%).

Experimental

Blümer et al. · OpenAlex - Early Childhood · 7 Oct 2026

Survival

Problem

Peanut allergy in children, especially those with high Ara h 2-sIgE who may have more adverse reactions and treatment failure with oral immunotherapy

Intervention: Peanut oral immunotherapy with low-dose initiation and slow up-dosing, with longitudinal monitoring of basophil activation and sIgE/sIgG4 as possible biomarkers
Population: 32 peanut-allergic children: 16 with high Ara h 2-sIgE (≥40 kU/L) and 16 with lower Ara h 2-sIgE

Key finding

Effective desensitization was achieved in 68.8% of the high-sIgE group and 62.5% of the lower-sIgE group.

Pre/post

Chen et al. · OpenAlex - Early Childhood · 7 Oct 2026

SurvivalDevelopment

Problem

Poor access to quality basic health and education services, with continuing child malnutrition, infant mortality and weak learning quality, especially in rural and remote areas of Indonesia

Intervention: Generasi programme, implemented for nine years (programme details are not given in the text)
Population: Households, village heads, and school and health facility staff in Generasi areas of Indonesia; over 46,000 people surveyed in the final round

Key finding

No impact results are reported in the text provided.

Pre/post

World Bank documents and reports · 1 May 2018

Survival

Problem

Childhood stunting and the lifetime income losses it causes

Intervention: A package of 10 nutrition interventions scaled up gradually over 10 years
Population: Children in 34 developing countries that account for 90 percent of the world's stunted children (modelled, not a studied sample)

Key finding

Estimated rate of return of 17 percent from phasing in the package over 10 years in 34 countries

Practitioner

World Bank documents and reports · 1 Aug 2018

Survival

Problem

Weak delivery of public health services, which communities can help improve by monitoring them (child health is the focus of the earlier studies cited).

Intervention: Government-led social accountability: giving communities information about health services, with or without facilitation of Village Health, Sanitation and Nutrition Committee (VHSNC) meetings.
Population: Communities in two districts of Uttar Pradesh, India, under the Uttar Pradesh Health Systems Strengthening Project.

Key finding

Information and facilitation jointly have larger effects than provision of information alone.

Experimental

World Bank documents and reports · 20 Sept 2018

Survival

Problem

Infants under 6 months who are malnourished, growing poorly, underweight, born too early or too small are at risk of death, illness and poor development, and care for them is mostly inpatient-only.

Intervention: The MAMI Care Pathway Package, an integrated outpatient care pathway with adaptable resources for at-risk infants under 6 months and their mothers, delivered within health services.
Population: At-risk infants under 6 months and their mothers, plus health workers, research staff, fathers and policymakers, in outpatient health facilities in Ethiopia.

Key finding

Staff perceived the pathway as feasible in outpatient services with additional structural support and likely acceptable to mothers.

Practitioner

McGrath · OpenAlex · 8 Oct 2026

Survival

Problem

High under-five mortality in rural Liberia among children living far from health facilities

Intervention: National Community Health Assistant Program (NCHAP), which provides primary health care through community health assistants to residents living more than 5 km from a health facility, rolled out two districts at a time
Population: Women and their children under five in the program catchment area of rural Grand Bassa County, Liberia (22,315 women, 32,743 children)

Key finding

No difference in under-five mortality between before and under-intervention periods (adjusted HR 1.03, 95% CI 0.82-1.31).

Experimental

Obaje et al. · OpenAlex · 28 Sept 2026

Survival

Problem

Low maternal compliance with the basic infant immunization schedule, leaving coverage below the national target in the Grogol Primary Health Center area

Intervention: Automated Google Calendar-based immunization reminders sent to mothers
Population: 60 mothers of infants aged 0-9 months in Grogol, Kediri Regency, Indonesia (30 intervention, 30 control), selected by purposive sampling

Key finding

Intervention group compliance increased from 46.7% to 83.3% (p=0.013).

Experimental

Adityarie et al. · OpenAlex · 29 Sept 2026

Survival

Problem

Maternal and neonatal morbidity and preventable maternal deaths in rural India, linked to sepsis, severe anaemia, delayed referral and inadequate emergency obstetric care

Intervention: Strengthened CEmONC services at a Community Health Centre, including emergency case management, a telephonic follow-up system for high-risk pregnancies, respectful maternity care through innovative discharge practices, and strengthened institutional delivery services
Population: Pregnant women and newborns attending CHC Faridpur, Bareilly, Uttar Pradesh, India

Key finding

The authors report favourable maternal and neonatal outcomes in the described cases.

Practitioner

Gautam et al. · OpenAlex · 29 Sept 2026

Survival

Problem

Hospitalization of infants for RSV bronchiolitis, and whether protection from nirsevimab differs by RSV lineage

Intervention: Immunization of infants with nirsevimab, a monoclonal antibody against RSV, implemented in France from September 2023
Population: Children younger than 12 months hospitalized with bronchiolitis in 12 French hospitals during the 2023–24 and 2024–25 RSV seasons

Key finding

Adjusted effectiveness against hospitalization for bronchiolitis was 88.4% (95% CI 84.5–91.4) with RSV-B.

Practitioner

Barbier et al. · OpenAlex · 29 Sept 2026

Survival

Problem

Uncertain parental acceptance of postnatal RSV monoclonal antibody immunisation for infants, which affects uptake and protection against infant RSV illness and hospitalisation

Intervention: Online messages giving information on the timing of the injection (shortly after birth) and on disease burden, with six variants compared against a control with no additional information
Population: UK parents of children under 18 years (survey sample of 12,326)

Key finding

Information that the mAb would be administered shortly after birth reduced post-exposure intent relative to control.

Experimental

Happenhofer et al. · OpenAlex · 29 Sept 2026

Survival

Problem

High diphtheria incidence among children in the Kazakh SSR at the end of the 1950s

Intervention: Mass diphtheria immunisation of children, supported by laboratory surveillance, early diagnosis, hospitalisation and timely treatment
Population: Population of the Kazakh SSR, with a focus on children, across regions, urban and rural areas and age groups

Key finding

Registered cases fell from 10,733 in 1959 to about 7,500 in 1960 and to roughly half that in 1961.

Practitioner

Mazhitova et al. · OpenAlex · 30 Sept 2026

Evidence on children's well-being, problem first.

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Evidence on children's well-being, problem first.